There are some differences and they are significant.
The US is not on a gold standard, so the devaluation of the dollar does not have to occur in a stepwise function with an official restatement of value. This time the Fed can simply monetize debt and provide more dollars as it wills. That is fiat.
The US is not a net exporter to the world, as it was then. This is why Smoot-Hawley was harmful to the US recovery. The major nations of the world, such as Germany, Italy, and Japan, became engaged in their own domestic industrial recovery including rearmament. Today the US is the consumer for the world's exporting nations. And it also owns the reserve currency.
The New Deal was a bottom up Jobs Program. The Deal this time is a new version of trickle down. The second wave down in the Great Depression caught many of the professionals who had made millions shorting the initial market declines, or at least survived the Great Crash by selling early. The next wave down in the current credit collapse is going to boil the middle class, a few degrees at a time.
Geither: None Would Have Survived - Rolfe Winkler
"He will wipe every tear from their eyes. There will be no more death, or mourning, or crying out in pain, for the old order of things will pass away. 'I am the Alpha and the Omega, the Beginning and the End. I will give you to drink freely from the springs of the water of life. All those who are faithful and persevere will inherit my creation. And I will be their Father, and they will be my children."
Revelation 21:3-7