"Besides replicating very quickly, the 1918 strain seems to trigger a particularly intense response from the immune system, including a ‘cytokine storm’ – the rapid release of immune cells and inflammatory molecules.
Although a robust immune response should help us fight infection, an over-reaction of this kind can overload the body, leading to severe inflammation and a build-up of fluid in the lungs that could increase the chance of secondary infections.
The cytokine storm might help to explain why young, healthy adults – who normally find it easier to shake off flu – were the worst affected, since in this case their stronger immune systems created an even more severe cytokine storm."
BBC, Why the Flu of 1918 Was So Deadly
"The world needs a new generation of policymakers who don’t hobnob with billionaire speculators and who understand workers’ concerns. Unfortunately, the change will not come smoothly. Political turmoil in the West is very much about this. A heavy price has to be paid to bring about the change."
Andy Xie, SCMP 21 Sept 2018