"Besides replicating very quickly, the 1918 strain seems to trigger a particularly intense response from the immune system, including a ‘cytokine storm’ – the rapid release of immune cells and inflammatory molecules.
Although a robust immune response should help us fight infection, an over-reaction of this kind can overload the body, leading to severe inflammation and a build-up of fluid in the lungs that could increase the chance of secondary infections.
The cytokine storm might help to explain why young, healthy adults – who normally find it easier to shake off flu – were the worst affected, since in this case their stronger immune systems created an even more severe cytokine storm."
BBC, Why the Flu of 1918 Was So Deadly
“Thus, it should be understood that when pro-US figures use the term, 'rules-based international order,' they are not referring to anything analogous to the rule of law. Quite the opposite, they are using Orwellian language to describe a system in which essentially no rules can be established and/or observed, given that the dominant state has the prerogative to violate and/or rewrite “rules” at its whim.” Aaron Good, American Exception